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Micro/Nanofluidics Laboratory: Research Interests

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Cartoon of high-pressure injector operation (place mouse on image to animate). Flow of mobile phase from left is forced through the separation column at top. Pressure pulses at right cause a fluoropolymer switch(blue) to move to left, closing the mobile phase line off from the system and connecting the sample fluid (green) to the separation column. After a small volume of sample (~200 pL) is injected, the fluoropolymer switch returns to its original position, and a chromatographic separation is performed at high pressure. This high-pressure microfluidic control element is created using laser-polymerization.
A microfluidic device incorporating liposome-based biosensing.
Top: Collision rates of cells in obstacle arrays as a function of row offsets. Straight arrays (yellow) lead to low cancer cell capture efficiency (bottom left) whereas GEDI arrays (refs here and here) lead to high cancer cell capture efficiency (bottom right).