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Stress-strain curve of tissue-engineered scaffolds used for seeding chondrocytes. We are designing biomaterials with controlled material properties so as to enable studies of mechanotransduction in chondrocytes during physiological loading.
6mm disks of tissue-engineered cartilage produced by culturing bovine articular chondrocytes in a photocrosslinked alginate matrix. We are interested in the electrokinetic properties of these matrices and the effects of these properties on tissue development.